Institutional review boards are almost universally considered to be overworked and understaffed. They also require substantial commitments of time and resources from their members. Although some surveys report average IRB memberships of 15 people or more, federal regulations require only five. We present data on IRB meetings at eight of the top 25 academic medical centers in the United States funded by the National Institutes of Health. These data indicate substantial contributions from primary reviewers and chairs during protocol discussions but (...) little from other members, which implies that it may be possible for smaller IRBs to accomplish the same tasks with no reduction in the quality of review. (shrink)

Mountaineering is a dangerous activity. For many mountaineers, part of its very attraction is the risk, the thrill of danger. Yet mountaineers are often regarded as reckless or even irresponsible for risking their lives. In this paper, we offer a defence of risk-taking in mountaineering. Our discussion is organised around the fact that mountaineers and non-mountaineers often disagree about how risky mountaineering really is. We hope to cast some light on the nature of this disagreement – and to argue that (...) mountaineering may actually be worthwhile because of the risks it involves. Section 1 introduces the disagreement and, in doing so, separates out several different notions of risk. Sections 2–4 then consider some explanations of the disagreement, showing how a variety of phenomena can skew people's risk judgements. Section 5 then surveys some recent statistics, to see whether these illuminate how risky mountaineering is. In light of these considerations, however, we suggest that the disagreement is best framed not simply in terms of how risky mountaineering is but whether the risks it does involve are justified. The remainder of the paper, sections 6–9, argues that risk-taking in mountaineering often is justified – and, moreover, that mountaineering can itself be justified by and because of the risks it involves. (shrink)

Mountaineering is a dangerous activity. For many mountaineers, part of its very attraction is the risk, the thrill of danger. Yet mountaineers are often regarded as reckless or even irresponsible for risking their lives. In this paper, we offer a defence of risk-taking in mountaineering. Our discussion is organised around the fact that mountaineers and non-mountaineers often disagree about how risky mountaineering really is. We hope to cast some light on the nature of this disagreement – and to argue that (...) mountaineering may actually be worthwhile because of the risks it involves. Section 1 introduces the disagreement and, in doing so, separates out several different notions of risk. Sections 2–4 then consider some explanations of the disagreement, showing how a variety of phenomena can skew people's risk judgements. Section 5 then surveys some recent statistics, to see whether these illuminate how risky mountaineering is. In light of these considerations, however, we suggest that the disagreement is best framed not simply in terms of how risky mountaineering is but whether the risks it does involve are justified. The remainder of the paper, sections 6–9, argues that risk-taking in mountaineering often is justified – and, moreover, that mountaineering can itself be justified (in part) by and because of the risks it involves. (shrink)

forthcoming in M. McNamee (ed) Philosophy, Risk and Adventure Sports, Routledge The final draft of a co-authored article with Simon Robertson (Leeds). In this paper we examine a recent version of an old controversy within climbing ethics. Our organising topic is the ‘bolting’….

This chapter contains sections titled: What is Self‐Sufficiency? The Value of Self‐Sufficiency Objections Concluding Remarks Notes.

Doctors routinely refuse donation offers from prospective living kidney donors with certain comorbidities such as diabetes or obesity out of concern for donor wellbeing. This refusal occurs despite the ongoing shortage of kidney transplants and the superior performance of living donor kidney transplants compared to those from deceased donors. In this paper, we argue that this paternalistic refusal by doctors is unjustified and that, within limits, there should be greater acceptance of such donations. We begin by describing possible weak and (...) strong paternalistic justifications of current conservative donor acceptance guidelines and practices. We then justify our position by outlining the frequently under-recognised benefits and the routinely overestimated harms of such donation, before discussing the need to respect the autonomy of willing donors with certain comorbidities. Finally, we respond to a number of possible objections to our proposal for more liberal kidney donor acceptance criteria. We use the situation in Australia as our case study, but our argument is applicable to comparable situations around the world. (shrink)

Auditory feedback perturbation studies have indicated a link between feedback and feedforward mechanisms in speech production when participants compensate for applied shifts. In spectral perturbation studies, speakers with a higher perceptual auditory acuity typically compensate more than individuals with lower acuity. However, the reaction to feedback perturbation is unlikely to be merely a matter of perceptual acuity but also affected by the prediction and production of precise motor action. This interplay between prediction, perception, and motor execution seems to be crucial (...) for the timing of speech and non-speech motor actions. In this study, to examine the relationship between the responses to temporally perturbed auditory feedback and rhythmic abilities, we tested 45 adult speakers on the one hand with a temporal auditory feedback perturbation paradigm, and on the other hand with rhythm perception and production tasks. The perturbation tasks temporally stretched and compressed segments (onset + vowel or vowel + coda) in fluent speech in real-time. This technique sheds light on the temporal representation and the production flexibility of timing mechanisms in fluent speech with respect to the structure of the syllable. The perception tasks contained staircase paradigms capturing duration discrimination abilities and beat-alignment judgments. The rhythm production tasks consisted of finger tapping tasks taken from the BAASTA tapping battery and additional speech tapping tasks. We found that both auditory acuity and motor stability in finger tapping affected responses to temporal auditory feedback perturbation. In general, speakers with higher auditory acuity and higher motor variability compensated more. However, we observed a different weighting of auditory acuity and motor stability dependent on the prosodic structure of the perturbed sequence and the nature of the response as purely online or adaptive. These findings shed light on the interplay of phonological structure with feedback and feedforward integration for timing mechanisms in speech. (shrink)

Highlighting the sources, processes and outcomes of moral struggles in and around markets, this volume advances our current understanding of markets and their contested moralities.

Background People who are at elevated risk of suicide stand to benefit from internet-based interventions; however, research in this area is likely impacted by a range of ethical and practical challenges. The aim of this study was to examine the ethical issues and practical barriers associated with clinical studies of internet-based interventions for suicide prevention. Method This was a mixed-methods study involving two phases. First, a systematic search was conducted to identify studies evaluating internet-based interventions for people at risk of (...) suicide, and information pertaining to safety protocols and exclusion criteria was extracted. Second, investigators on the included studies were invited to complete an online survey comprising open-ended and forced-choice responses. Quantitative and qualitative methods were used to analyse the data. Results The literature search identified 18 eligible studies, of which three excluded participants based on severity of suicide risk. Half of the 15 suicide researchers who participated in the survey had experienced problems obtaining ethics approval, and none had encountered adverse events attributed to their intervention. Survey respondents noted the difficulty of managing risk in online environments and the limitations associated with implementing safety protocols, although some also reported increased confidence resulting from the ethical review process. Respondents recommended researchers pursue a collaborative relationship with their research ethics committees. Conclusion There is a balance to be achieved between the need to minimise the risk of adverse events whilst also ensuring interventions are being validated on populations who may be most likely to use and benefit from them. Further research is required to obtain the views of research ethics committees and research participants on these issues. Dialogue between researchers and ethics committees is necessary to address the need to ensure safety while also advancing the timely development of effective interventions in this critical area. (shrink)

Two experiments investigated inferences based on suppositions. In Experiment 1, the subjects decided whether suppositions about individuals' veracity were consistent with their assertions—for example, whether the supposition “Ann is telling the truth and Beth is telling a lie”, is consistent with the premises: “Ann asserts: I am telling the truth and Beth is telling the truth. Beth asserts: Ann is telling the truth”. It showed that these inferences are more difficult than ones based on factual premises: “Ann asserts: I live (...) in Dublin and Beth lives in Dublin”. There was no difference between problems about truthtellers and liars, who always told the truth or always lied, and normals, who sometimes told the truth and sometimes lied. In Experiment 2, the subjects made inferences about factual matters set in three contexts: a truth-inducing context in which friends confided their personality characteristics, a lie-inducing context in which business rivals advertised their products, and a neutral context in which computers printed their program characteristics. Given the supposition that the individuals were lying, it was more difficult to make inferences in a truth-inducing context than in the other two contexts. We discuss the implications of our results for everyday reasoning from suppositions, and for theories of reasoning based on models or inference rules. (shrink)

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

This chapter outlines three programs that aim to use biological insights in support of philosophical positions in ethics: Aristotelian approaches found, for example, in Thomas Hurka and Philippa Foot; Humean approaches found in Simon Blackburn and Allan Gibbard; and biologically grounded approaches found in of Elliott Sober and Brian Skyrms. The first two approaches begin with a philosophical view, and seek support for it in biology. The third approach begins with biology, and uses it to illuminate the status of (...) morality. This chapter pursues a version of the third program. A major accomplishment of evolutionary biology has been the explanation of biological altruism, which opens the door to a similar explanation of psychological altruism, or “fellow-feeling.” The chapter conjectures that humans have evolved a capacity for normative governance by socially shared rules. A process of cultural evolution led to the social rules with which we are familiar. This genealogical story poses a challenge, for the idea of moral truth plays no role in it. The story therefore lends support to non-cognitivism or anti-realist expressivism. The chapter concludes by exploring the implications of the genealogical story for moral knowledge, moral objectivity, and the idea of moral authority. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

We study the handicap principle in terms of the Sir Philip Sidney game. The handicap principle asserts that cost is required to allow for honest signalling in the face of conflicts of interest. We show that the significance of the handicap principle can be challenged from two new directions. Firstly, both the costly signalling equilibrium and certain states of no communication are stable under the replicator dynamics ; however, the latter states are more likely in cases where honest signalling (...) should apply. Secondly, we prove the existence and stability of polymorphisms where players mix between being honest and being deceptive and where signalling costs can be very low. Neither the polymorphisms nor the states of no communication are evolutionarily stable, but they turn out to be more important for standard evolutionary dynamics than the costly signalling equilibrium. (shrink)

Game theory has a prominent role in evolutionary biology, in particular in the ecological study of various phenomena ranging from conflict behaviour to altruism to signalling and beyond. The two central methodological tools in biological game theory are the concepts of Nash equilibrium and evolutionarily stable strategy. While both were inspired by a dynamic conception of evolution, these concepts are essentially static—they only show that a population is uninvadable, but not that a population is likely to evolve. In this article, (...) we argue that a static methodology can lead to misleading views about dynamic evolutionary processes. We advocate, instead, a more pluralistic methodology, which includes both static and dynamic game theoretic tools. Such an approach provides a more complete picture of the evolution of strategic behaviour. 1 Introduction2 The Equilibrium Methodology3 Common Interest Signalling3.1 Lewis’s signalling game3.2 Static analysis3.3 Dynamic analysis4 The Sir Philip Sidney Game4.1 Static analysis4.2 Other equilibria4.3 Dynamic analysis5 Related Literature6 Static and Dynamic Approaches. (shrink)

In Science, Truth, and Democracy, Philip Kitcher challenges the view that science has a single, context‐independent, goal, and that the pursuit of this goal is essentially immune from moral critique. He substitutes a context‐dependent account of science’s goal, and shows that this account subjects science to moral evaluation. I argue that Kitcher’s approach must be modified, as his account of science ultimately must be explicated in terms of moral concepts. I attempt, therefore, to give an account of science’s goal (...) that is free of direct moral entanglements but still makes this goal context‐dependent and leaves the choice of which projects to pursue subject to moral scrutiny. (shrink)

This volume documents the 16th Münster Lectures in Philosophy and examines five themes that are prominent in the work of philosopher and political theorist Philip Pettit. These themes are: Epistemology and Semantics, Philosophy of Mind, Consequentialism, Group Agency, and Republicanism. The book provides insight into Pettit's work and demonstrates the central role his work plays in a number of contemporary philosophical debates. Pettit’s contributions to the philosophy of mind and action, rational choice theory, the philosophy of the social sciences, (...) as well as metaethics, normative ethics and political philosophy are main points of reference, and have advanced ongoing and initiated new discussions. The book shows that a striking feature of Pettit's work has been the depth of his analyses and arguments regarding individual topics – ranging from rule-following to free will, from group agency to social ontology and the methodology of the social sciences, from a defense of consequentialism to the revival of the republican tradition in the theory of democracy and to value theory, but also their systematic overall coherence. The book contains Pettit’s lecture "Freedom and Other Robustly Demanding Goods", nine critical papers on Pettit’s philosophy, and a reply article entitled "Self-Defense on Five Fronts: A Reply to My Commentators". (shrink)

This chapter focuses on the important role played by landscape in the Christian religious imagination. It argues for the ambiguity of “landscape” in the sense that locales like forests, fields, and mountains are both geographic realities and imaginary realities. Many locales are considered powerful symbols of fear or desire. According to Simon Schama’s Landscape and Memory, “Landscapes are culture before they are nature; constructs of the imagination projected onto wood and water and rock.” This means that landscape is irreducibly (...) historical since it portrays the material world mediated through human experience. It is also inevitably linked with issues of power because it provides the physical features upon which human beings draw and shape unique identities and distinct worldviews. (shrink)

The Great Philosophers, From Thales of Miletus (ca. 620-540 b.c.), "The first natural scientist and analytical philosopher in Western intellectual history," to W.V.O. Quine (1908-2000): "Only science can tell us the truth about the world" Philosophy is a thorough and accessible introduction to the Western intellectual tradition, covering philosophical, scientific, and religious thought over a period of 2,500 years. Offering brief summaries of the work of Socrates, Plato, and Aristotle, as well as Copernicus, Machiavelli, Galileo, Spinoza, Voltaire, Adam Smith, Mary (...) Wollstonecraft, Thomas Paine, Darwin, Marx, Freud, Simone de Beauvoir, Levi-Strauss, and Einstein, to name just a few, this book will serve as an invaluable guide for those seeking a clear introduction to the work of individual philosophers. A lucid and engaging book, Philosophy is sure to stimulate and absorb students and laymen alike. (shrink)

_"A genial exercise in public philosophy" (_Kirkus_, starred review) from one of the world's best-known popular philosophers__ "Simon Critchley is an international treasure—that rare and real philosopher who embraces Rousseau’s ‘feeling of existence,’ David Bowie’s vision of love, and Philip K. Dick’s genius with genuine wrestling and a soulful smile!’’—Cornel West, Harvard University_ The moderator of the _New York Times_’ Stone column and the author of numerous books on everything from Greek tragedy to David Bowie, Simon Critchley (...) has been a strong voice in popular philosophy for more than a decade. This volume brings together thirty-five essays, originally published in the _Times,_ on a wide range of topics, from the dimensions of Plato’s academy and the mysteries of Eleusis to Philip K. Dick, Mormonism, money, and the joy and pain of Liverpool Football Club fans. In an engaging and jargon‑free style, Critchley writes with honesty about the state of world as he offers philosophically informed and insightful considerations of happiness, violence, and faith. Stripped of inaccessible academic armatures, these short pieces bring philosophy out of the ivory tower and demonstrate an exciting new way to think in public. (shrink)

If the import of a book can be assessed by the problem it takes on, how that problem unfolds, and the extent of the problem’s fruitfulness for further exploration and experimentation, then Duffy has produced a text worthy of much close attention. Duffy constructs an encounter between Deleuze’s creation of a concept of difference in Difference and Repetition (DR) and Deleuze’s reading of Spinoza in Expressionism in Philosophy: Spinoza (EP). It is surprising that such an encounter has not already been (...) explored, at least not to this extent and in this much detail. Since the two works were written simultaneously, as Deleuze’s primary and secondary dissertations, it is to be expected that there is much to learn from their interaction. Duffy proceeds by explicating, in terms of the differential calculus, a logic of what Deleuze in DR calls different/ciation, and then maps this onto Deleuze’s account of modal expression in EP. (shrink)

The French philosopher Simone Weil worked on (but did not finish) Venice Saved, a tragedy about the conspiracy to overthrow the Republic of Venice in 1618. It has been largely ignored and has never been published in an English translation. Interest in Weil’s work has increased massively since her death and continues to grow, so that publishing this play in English will enable readers to expand their view of a writer whose work is in fragments. We have also translated the (...) notes that Weil wrote about Venice Saved and her sketches for the unwritten scenes, and have written four introductory chapters on: Weil’s life and significance; how the play came to be written and what it has to say; Weil’s view of tragedy; the issues raised by writing an English version of this play. There are endnotes, suggestions for further reading, and a bibliography of all works used in writing the introductory material. (shrink)

This paper considers the relation between mytho-poetic narrative and practical philosophy in an Idealist/Romantic fragment, usually attributed to Hegel, known as the ‘System-programme’. Like many works of the young Hegel, the text seeks political reform through a reform of religion and suggests that for politics to be truly motivating reason must be embedded in mytho-poetic discourse. This Hegelian ‘reform’ is in the service of a new, sensuous, practical rationality and a motivating political praxis. The paper places these issues in the (...) context of the religious thought of J.J. Rousseau, particularly his religious themes, as presented in The Social Contract . The paper also connects these issues to a political problem identified in recent work by Simon Critchley, the problem of practical or moral motivation. Critchley claims that while citizens of secular, liberal, democratic societies experience the political norms that shape their lives as externally binding, these norms are not internally compelling. Against this he claims that what are motivating are frameworks of belief that call the secular project into question. At least one of Critchley’s solutions to this problem is connected to the sphere of the religious. While accepting the idea that connecting social and political problems to religion can render them motivating, this paper will withhold from endorsing either the solution offered by the young Hegel in the ‘System-programme’ or Critchley’s, and raises doubts also about the Rousseauian response . It argues that these solutions fail to adequately address the problem they face: how to render contemporary political life internally compelling for modern political subjects? (shrink)

Welfare states are in a care crisis both in the sense of a practical care gap and in the new movement to limit care to mere rehabilitation. Few political theorists pay attention to these developments, and those who do say little about the potential limits to care. This article discusses Philip Pettit’s theory of social justice in relation to questions of public care provisions. Pettit’s theory has been praised by feminists for its attention to social injustices and because it (...) highlights fair limits to care. The article examines how Pettit builds up his argument involving the idea of a gateway good, heuristics and a set of constraints. Although the article points to the value of Pettit’s theory, Pettit’s arguments to limit the state’s care tasks depend on the false assumption that a theory of justice considers able-minded adults only. This article argues that Pettit’s assumption that we leave out children and not-so-able-minded elderly leads to a general neglect o... (shrink)

This book challenges the dominant approach to problems of justice in global normative theory and offers a radical alternative designed to transform our thinking about what kind of problem injustice is and how political theorists might do better in understanding and addressing it. It argues that the dominant approach, ideal moral theory (IMT), takes a fundamentally wrong-headed approach to the problem of justice. IMT seeks to work out what an ideally just society would look like, and only then outlines our (...) moral obligations in realizing that ideal. In other words, it ignores the realities of everyday politics. As Michael Goodhart asserts, IMT postpones engagement with actually existing injustices and distorts our understanding of them, and it normalizes many problematic features of our world. On the other hand, the leading alternatives to IMT struggle to make sense of the role values play in politics. This book sees justice as an ideology and develops an innovative bifocal theoretical framework for making sense of it. This framework provides two complementary perspectives on justice: a theoretical perspective that situates competing ideological claims about justice in a broader political context and a partisan perspective that evaluates the structure and coherence of particular conceptions of justice. As opposed to IMT, it focuses on barriers to justice and advocates an activist political theory that takes sides in political struggles against injustice. Goodhart argues that theorists can help to generate the countervailing power necessary for social transformation through the work of articulation, translation, and mapping, work which contributes to a more comprehensive social science of injustice. (shrink)

Research on personality psychology is making important contributions to psychological science and applied psychology. This second edition of The Cambridge Handbook of Personality Psychology offers a one-stop resource for scientific personality psychology. It summarizes cutting-edge personality research in all its forms, including genetics, psychometrics, social-cognitive psychology, and real-world expressions, with informative and lively chapters that also highlight some areas of controversy. The team of renowned international authors, led by two esteemed editors, ensures a wide range of theoretical perspectives. Each research (...) area is discussed in terms of scientific foundations, main theories and findings, and future directions for research. The handbook also features advances in technology, such as molecular genetics and functional neuroimaging, as well as contemporary statistical approaches. An invaluable aid to understanding the central role played by personality in psychology, it will appeal to students, researchers, and practitioners in psychology, behavioral neuroscience, and the social sciences. (shrink)

In this chapter, we consider ethical and philosophical aspects of trust in the practice of medicine. We focus on trust within the patient-physician relationship, trust and professionalism, and trust in Western (allopathic) institutions of medicine and medical research. Philosophical approaches to trust contain important insights into medicine as an ethical and social practice. In what follows we explain several philosophical approaches and discuss their strengths and weaknesses in this context. We also highlight some relevant empirical work in the section on (...) trust in the institutions of medicine. It is hoped that the approaches discussed here can be extended to nursing and other topics in the philosophy of medicine. (shrink)